Greater Manchester

Inflammation and Repair Research Domain

Manchester is internationally recognised as a centre of expertise for research into inflammation and repair. We translate our interdisciplinary excellence in inflammation and regenerative medicine research and education into the highest quality, multi-professional care for patients with inflammatory diseases.

The domain works closely with The University of Manchester’s Infection, immunity, inflammation and repair strategic research domain. This spans basic, clinical and translational innovation at the interface of infection, immunity, inflammation and repair. Basic Science research is carried out in many divisions across the School of Biological Sciences, including Manchester Collaborative Centre for Inflammation and RepairArthritis Research UK Centres of Excellence in Genetics and Genomics, and Epidemiology, and in the Manchester Fungal Infection Group.

We also introduce new collaborative centres – designed to bring experts in academia and healthcare to work on innovative new treatments and ways of delivering care – and take advantage of some of the excellent facilities in Manchester.

We are leaders in stratified medicine, an approach that divides patients with a particular disease according to how they respond to therapies. The aim is to get the right treatment to the right person at the right time. We have significantly increased our stratified medicine infrastructure through the NIHR Manchester Biomedical Research Centre, the Manchester Molecular Pathology Innovation Centre with a focus on immune-mediated conditions, the Stoller Biomarker Discovery Centre and three Medical Research Council Stratified Medicine Consortia (Rheumatoid ArthritisPsoriasis and Systemic Lupus Erythematosus ).

In our NIHR Manchester Biomedical Research Centre, we are driving forward pioneering research into new tests and treatments in musculoskeletal diseasehearing healthrespiratory diseasedermatology and three cancer themes (prevention, radiotherapy and precision medicine), utilising our expertise in biomarkers, informatics and the rapid translation of research findings.

Our domain works across these areas:

New initiatives include:

Rheumatology Virtual Clinic

The impact of a Virtual Biologics Clinic (VBC) on patient experience, research recruitment, and drug budget: a Quality Improvement Project.

The Manchester Psoriasis Shout Out!

Get it Right First Time – Improving the Quality of Orthopaedic Care within the National Health Service in England

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